Baseline-ZERO™ DNase, 5,000 Units

Baseline-ZERO™ is able to:

• effectively digest large or small dsDNA and ssDNA into mononucleotides, more effectively, than commonly used bovine pancreatic DNase I. Small DNA oligonucleotides that remain after treatment with bovine pancreatic DNase I are undetectable by gel electrophoresis following treatment with Baseline-ZERO DNase.
• Digest unwanted dsDNA and ssDNA molecules including small ssDNA such as random hexamers
• Use in sensitive applications requiring reverse transcription where any contaminating DNA is unwanted

Applications:

• Removal of genomic DNA from small-sample total RNA preparations for expression analysis (below graph)
• Removal of small DNA oligonucleotides (e.g., random primers)

More information for Baseline-ZERO™

DNase protocol

Enzymes catalogue