ClearColi® BL21(DE3) Electrocompetent Cells, 12R (DUOS)

A better way to eliminate endotoxin contamination

ClearColi® BL21(DE3) cells are the first commercially available competent cells with a modified lipopolysaccharide (LPS) that does not trigger the endotoxic response in mammalian cells.  This means that instead of removing lipopolysaccharide (LPS) contamination from your protein or plasmid DNA preparations, the LPS  can be eliminated at the source.   Read more

Features & Benefits

• Genetically modified LPS that does not trigger an endotoxic response in human cells
• Ideal for mammalian cell immunogenicity testing, toxicity assays, and therapeutic protein drug discovery
• Useful for membrane and lipid-binding protein production
• Protein expression similar to BL21(DE3) cells without requiring downstream endotoxin removal
• Reduce false positives in cytokine assays, improve confidence in your results

Full protocol

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