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Locked nucleic acid (LNA) Probes
LNAs are modified RNA bases in which the ribose is “locked” with a methylene bridge, connecting the 2′ oxygen atom to the 4′ carbon atom, fixing it in the C3′-endo conformation. Improve assay sensitivity and specificity with these probes from LCG Biosearch.
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Product Details
Improve assay sensitivity and specificity with locked nucleic acid (LNA) oligonucleotides. LNAs are modified RNA bases in which the ribose is “locked” with a methylene bridge, connecting the 2′ oxygen atom to the 4′ carbon atom, fixing it in the C3′-endo conformation.
The LNA’s have a shorter probe which means:
- Improved assay sensitivity
- Higher quenching efficiency (lower background)
- Greater signal-to-noise ratio
- Increased hybridisation specificity
- Targeting A-T rich sequences
- Better mismatch discrimination in SNP genotyping assays
Read more about the LNA probes here
Take advantage of our consolidated ordering process to make ordering easy and cost effective.
Every Friday we collate orders for primers & probes and send them to our supplier, LGC Biosearch. Simply download the order form below, fill it it in and send to [email protected]
We place the order and send to you once it’s arrived so you don’t need to worry about international courier fees or customs clearance.
